{"id":36,"date":"2003-07-15T10:31:55","date_gmt":"2003-07-15T01:31:55","guid":{"rendered":"http:\/\/unknowngenius.com\/blog\/archives\/2003\/07\/15\/natural-high\/"},"modified":"2007-04-17T18:40:42","modified_gmt":"2007-04-17T16:40:42","slug":"natural-high","status":"publish","type":"post","link":"https:\/\/unknowngenius.com\/blog\/archives\/2003\/07\/15\/natural-high\/","title":{"rendered":"Natural High"},"content":{"rendered":"<p>While doing some online medical research, I <b>accidentally<\/b> (I swear!) stumbled upon a <a href=\"http:\/\/cyberpharmacie.free.fr\/\">French <i>&#8220;Cyberpharmacie&#8221;<\/i><\/a> featuring, among other regular prescription drugs, a brief overview of recreational substances, their use, risk and chemical properties.<br \/>\n<!--more--><br \/>\nBeing the curious type, I read along and learnt one particularly interesting fact about <a href=\"http:\/\/www.erowid.org\/chemicals\/ghb\/ghb.shtml\">GHB<\/a> that I was totally unaware of. My favorite <a href=\"http:\/\/www.erowid.org\">substance information repository<\/a> bearing no mention of this fact, I remained dubitative and dug deeper on the net until I eventually found what appears to be a <a href=\"http:\/\/www.everything2.com\/index.pl?lastnode_id=16744&amp;node_id=943480\">rather reliable confirmation<\/a> <i>(note on the topic of &#8220;reliable internet information source&#8221;: there aren&#8217;t any. one can rely solely on common sense and gut feeling&#8230; but anyway: what&#8217;s to be relied on?)<\/i>. A few other searches into the chemicals and body metabolism involved brought a decent level of confirmation to it.<\/p>\n<p>So indeed, believe it or not:<br \/>\n<i>The human body is able to naturally synthesize gamma-Hydroxybutyrate (GHB) from its precursor gamma-Butyrolactone (GBL) through simple ingestion.<\/i><\/p>\n<p>So, if you take in account the fact that GBL is a rather commonly used substance in all kind of solvents and paint remover, you can roughly translate this fact into:<br \/>\n<i>Swallowing a few swigs of certain nail polish removers is akin to taking ghb and will get you seriously high<\/i><\/p>\n<p>I know, I know: &#8220;doh, like we didn&#8217;t know that ever since high school&#8230; paint solvents are funny things to breath&#8221; and so on&#8230;<\/p>\n<p>But let&#8217;s precise we are talking about a specific use (ingestion) and a very specific type of solvent (there are tons of other, more harmless, solvents. GBL is usually reserved to commercial applications, in part due to this property) turning into a <b>very serious<\/b> psychoactive substance widely known for its heavy recreational purposes&#8230;<\/p>\n<p>Another important side note is that, in order for it to be effectively synthesized into ghb, the gbl cannot be ingested with any water or water-based drinks&#8230; Which is a serious downside given its unbearably bad taste (ever tried to swallow nail polish? I would probably not).<\/p>\n<p>Anyway, just thought this was an interesting piece of informational bio-chemistry. What an endless source of mysteries and wonderment the human body is&#8230;<\/p>\n<p>Oh, and remember kids: <big>Winners Don&#8217;t Do Drugs<\/big> (they just sell them)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Interesting fact about GHB and human body ability to naturally synthesize it from GBL<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"activitypub_content_warning":"","activitypub_content_visibility":"","activitypub_max_image_attachments":4,"activitypub_interaction_policy_quote":"anyone","activitypub_status":"","footnotes":""},"categories":[7],"tags":[],"class_list":["post-36","post","type-post","status-publish","format-standard","hentry","category-better-living-through-chemistry"],"_links":{"self":[{"href":"https:\/\/unknowngenius.com\/blog\/wp-json\/wp\/v2\/posts\/36","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/unknowngenius.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/unknowngenius.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/unknowngenius.com\/blog\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/unknowngenius.com\/blog\/wp-json\/wp\/v2\/comments?post=36"}],"version-history":[{"count":0,"href":"https:\/\/unknowngenius.com\/blog\/wp-json\/wp\/v2\/posts\/36\/revisions"}],"wp:attachment":[{"href":"https:\/\/unknowngenius.com\/blog\/wp-json\/wp\/v2\/media?parent=36"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/unknowngenius.com\/blog\/wp-json\/wp\/v2\/categories?post=36"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/unknowngenius.com\/blog\/wp-json\/wp\/v2\/tags?post=36"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}